Propellerhead Reason jest dostępny w trzech wersjach: Reason, Reason Intro oraz wersja dostarczana razem z niektórymi instrumentami Reason Lite. Poniżej prezentujemy porównanie poszczególnych edycji:
| Reason Lite | Reason Intro | Reason | |
| Instrumenty | |||
| Europa Shapeshifting Synthesizer | T | T | T |
| Thor Polysonic Synthesizer | T | T | T |
| Subtractor Synthesizer | T | T | T |
| ID-8 Songwriter's Toolbox | T | T | T |
| Grain Sample Manipulator | T | ||
| Malström Graintable Synthesizer | T | ||
| Radical Piano | T | ||
| Klang Tuned Percussion | |||
| Pangea World Instruments | T | ||
| Humana Vocal Ensemble | T | ||
| Drums & loops | |||
| Kong Drum Designer | T | T | T |
| Dr. Octo Rex Loop Player | T | T | T |
| Redrum Drum Computer | T | T | T |
| Samplers | |||
| NN-XT Advanced Sampler | T | T | T |
| Live Sampling | T | T | T |
| NN19 Sampler | T | T | T |
| Device control | |||
| Player MIDI Devices | T | T | T |
| Combinator | T | T | T |
| Matrix Pattern Sequencer | T | T | T |
| Spider Mergers/Splitters | T | T | T |
| RPG-8 Arpeggiator | T | T | T |
| Dynamics/EQ | |||
| MClass EQ | T | T | T |
| MClass Compressor | T | T | T |
| MClass Maximizer | T | T | T |
| MClass Stereo Imager | T | T | T |
| Effects | |||
| RV7000 Advanced Reverb | T | T | T |
| Scream 4 Distortion | T | T | T |
| Audiomatic Retro Transformer | T | T | T |
| Softube Guitar/Bass Amps | T | T | T |
| Pulsar Dual LFO | T | T | T |
| DDL-1 Digital Delay | T | T | T |
| CF-101 Chorus/Flanger | T | T | T |
| The Echo | T | ||
| Synchronous Effect Modulator | T | ||
| Neptune Pitch Adjuster | T | ||
| BV512 Vocoder | T | ||
| Pulveriser Demolition Unit | T | ||
| Alligator Triple Filtered Gate | T | ||
| RV-7 Digital Reverb | T | ||
| D-11 Foldback Distortion | T | ||
| ECF-42 Envelope Controlled Filter | T | ||
| PH-90 Phaser | T | ||
| UN-16 Unison | T | ||
| COMP-01 Compressor/Limiter | T | ||
| PEQ-2 Two Band Parametric EQ | T | ||
| Mixer | |||
| Equalizer with Lo-pass/Hi-pass filters | T | T | T |
| Spectrum analyzer | T | T | T |
| Master Bus Compressor | T | T | T |
| Compressor | T | T | T |
| Gate | T | T | T |
| Send Effects | 8 send effects | 8 send effects | 8 send effects |
| Insert Effects | T | T | T |
| Group and parallel channels | T | T | T |
| Sound Banks | |||
| Factory Sound Bank | Very limited sound bank | Limited sound bank | Full sound bank |
| Orkester sound bank | T | ||
| Drum Supply sound bank | T | ||
| Loop Supply sound bank | T | ||
| Production | |||
| Audio Tracks | 8 total audio and/or instrument tracks | 16 total audio and/or instrument tracks | Unlimited |
| Instrument Tracks | 8 total audio and/or instrument tracks | 16 total audio and/or instrument tracks | Unlimited |
| Time stretch and slice edit | T | T | T |
| Pitch Edit | T | T | T |
| Audio Clip Transpose | T | T | T |
| Audio to MIDI | T | T | T |
| Blocks Song Arrangement | T | T | T |
| ReGroove Mixer | T | T | T |
| Creates REX files | T | T | T |
| Expandability | |||
| VST support | T | T | T |
| Rack Extension support | T | T | T |
| ReFill support | Limited support | Limited support | Limited support |
| Ableton Link | T | T | T |
| ReWire | T | ||
| MIDI out/MIDI clock out | T | T | T |